|
|
Current working Address:
Department of Anesthesiology, No 138 Sheng Li Road, National Cheng Kung University Medical College and Hospital, Tainan city 704, Taiwan
Education:
 Ph.D. National Sun Yat-Sen University, Kaohsiung, Taiwan
M.S, Physiology, Tzu Chi University, Hualien, Taiwan
M.D., National Yang Ming University, Taiwan
Current Position:
Professor, Department of Anesthesiology, National Cheng-Kung University, Taiwan 2018-
Director, Basic Anesthesia Research, Department of Anesthesiology, National Cheng-Kung University Hospital, Taiwan 2015-
Editorial Board, Taiwan Society of Anesthesiologists 2015-
Editor-in-Chief, The Taiwan Journal of Pain 2016-
Director, The Taiwan Journal of Pain 2019-
Experience:
Managing Supervisor, Taiwan Pain Society 2015-2017
Director, Department of Anesthesiology, National Cheng Kung University medical school and Hospital, Taiwan, 2011-2015
Associate Professor, Department of Anesthesiology, National Cheng Kung University, Taiwan, 2010-2018
Research fellow, Department of Anesthesiology, Brigham and Women’s Hospital, Harvard university, Boston, USA 2008-2010
Visiting Staff, Department of Anesthesiology, Kaohsiung Veteran General Hospital, Taiwan 2000 – 2004
Attending, Yu-Li Veteran Hospital, Hualien County, Taiwan. 1998-2000
Director, Quality and Safety committee, Taiwan Society of Anesthesiologists 2012-2014
Vice Director, Education committee in south Branch, Taiwan Society of Anesthesiologists 2012-2014
Secretary General, Taiwan Pain Society 2006-2008，2013-2015
Supervisor, Taiwan Pain Society 2012-2014
Director, Taiwan Society of Anesthesiologists 2012-2014
Proposition for High Special Technicians, Ministry of Examination, Taiwan 2015
Supervisor, Taiwan Society of Anesthesiologists 2014-2016
Director, Research development and promotion committee, Taiwan Society of Anesthesiologists 2014-2016
Vice Director, Specialist Accreditation committee, Taiwan Society of Anesthesiologists 2012-2016
Research Award:
Elite Aboard Research Program for the staffs in National Cheng Kung University Hospital 2008
The CASP Young Investigator Award, Chinese Association for the Study of Pain, CASP (Taiwan), 2010
Top 15 Basic Research Poster, Annual meeting of Taiwan society of Anesthesiologists, 2010
The CASP Research Prize, Chinese Association for the Study of Pain, CASP (Taiwan), 2011
Second best research oral presentation, Annual meeting of Taiwan Pain Society 2016, 2017 (Supervisor)
Top 5 poster presentation, The 7th Asian Pain Symposium, 2017
Field of Research Interesting:
Anesthesiology (anesthetics on pathological conditions)
Pain medicine (opioid and other analgesics)
Physiology (pain on physiological impact)
Journal Reviewer :
Acta Anaesthesiologica Taiwanica
The Chinese Journal of Pain (Taiwan)
Kaohsiung Journal of Medical Sciences
Journal of Microbiology, Immunology and Infection
TZU CHI Medical Journal (Taiwan)
Evidence-Based Complementary and Alternative Medicine
Case Reports in Anesthesiology
Oxidative Medicine and Cellular Longevity
Pain Medicine
Journal of Pharmacological Sciences
Publication List:(2011-)
1. HT Hsiao, YC Liu, PY Liu, SN Wu
Concerted suppression of Ih and activation of IK (M) by ivabradine, an HCN-channel inhibitor, in pituitary cells and hippocampal neurons.
Brain Research Bulletin. 2019 Apr 3;149:11-20.
2. YY Liu, HT Hsiao, JCF Wang, YC Liu, SN Wu
Parecoxib, a selective blocker of cyclooxygenase-2, directly inhibits neuronal delayed-rectifier K+ current, M-type K+ current and Na+ current.
European journal of pharmacology. 2019 Feb 5;844:95-101.
3. PC Wu, DB Shieh, HT Hsiao, JCF Wang, YC Lin, YC Liu
Magnetic field distribution modulation of intrathecal delivered ketorolac iron-oxide nanoparticle conjugates produce excellent analgesia for chronic inflammatory pain.
Journal of nanobiotechnology. 2018 May 16;16(1):49.
4. YC Lin, HT Hsiao, SN Wu, YC Liu
Huntington Mice Demonstrate Diminished Pain Response in Inflammatory Pain Model.
Anesthesia and analgesia. 2018 Feb;126(2):661-669.
5. PC Kuo, CJ Yang, YC Lee, PC Chen, YC Liu, SN Wu
The comprehensive electrophysiological study of curcuminoids on delayed-rectifier K+ currents in insulin-secreting cells.
European journal of pharmacology. 2018 Jan 15;819:233-241.
6. PC Wu, HT Hsiao, YC Lin, DB Shieh, YC Liu
The analgesia efficiency of ultrasmall magnetic iron oxide nanoparticles in mice chronic inflammatory pain model.
Nanomedicine: Nanotechnology, Biology and Medicine 2017 Aug;13(6):1975-1981.
7. Hung-Tsung Hsiao, Hsiao-Jung Chien, Ya-Chi Lin, Yen-Chin Liu.
Transcutaneous electrical nerve stimulator of 5000 Hz frequency provides better analgesia than that of 100 Hz frequency in mice muscle pain model.
Kaohsiung Journal of Medical Sciences (2017) 33, 165-170.
8. Hsiao HT, Lin YC, Wang JCF, Tsai YC, Liu YC.
Hypoxia inducible factor-1α inhibition produced anti-allodynia effect and suppressed inflammatory cytokine production in early stage of mouse complex regional pain syndrome model.
Clinical and Experimental Pharmacology and Physiology. 2016 Mar;43(3):355-9.
9. HT Hsiao, H Wu, PC Huang, YC Tsai, YC Liu.
The effect of propofol and sevoflurane on antioxidants and proinflammatory cytokines in a porcine ischemia-reperfusion model.
Acta Anaesthesiologica Taiwanica 54 (1), 6-10 2016.
10. Berta T, Park CK, Xu ZZ, Xie RG, Liu T, Lü N, Liu YC, Ji RR.
Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion.
J Clin Invest. 2014 Mar;124(3):
11. Berta T+, Liu YC+, Xu ZZ, Ji RR
Tissue plasminogen activator contributes to morphine tolerance and induces mechanical allodynia via astrocytic IL-1β and ERK signaling in the spinal cord of mice. 2013 Sep
Neuroscience. 2013;247:376-85 +These authors contributed equally to this work
12. Liu T, Berta T, Xu ZZ, Park CK, Zhang L, Lü N, Liu Q, Liu Y, Gao YJ, Liu YC, Ma Q, Dong X, Ji RR.
TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice.
J Clin Invest. 2012 Jun;122(6):2195-207
13. Liu YC, Wu PC, Shieh DB, Wu SN
The effects of magnetite (Fe3O4) nanoparticles on electroporation-induced inward currents in pituitary tumor (GH3) cells and RAW 264.7 macrophages. 2012 Mar
International Journal of nanomedicine 2012:7:1687-1696
14. Liu YC, Berta T, Liu T, Tan PH,Ji RR.
Acute morphine induces matrix metalloproteinase-9 up-regulation in primary sensory neurons to mask opioid-induced analgesia in mice
Mol Pain. 2012 Mar 25;8(1):19
15. Berta T, Liu T, Liu YC , Xu ZZ,Ji RR.
Acute morphine activates satellite glial cells and up-regulates IL-1beta in dorsal root ganglia in mice via matrix metalloprotease-9.
Mol Pain. 2012 Mar 22;8(1):18. doi: 10.1186/1744-8069-8-18.
16. Yeh CY, Chung SC, Tseng FL,Tsai YC, Liu YC.
Biphasic effects of chronic intrathecal gabapentin administration on the expression of protein kinase C gamma in the spinal cord of neuropathic pain rats.
Acta Anaesthesiol Taiwan. 2011 Dec;49(4):144-8.
17. Wen YR, Tan PH, Cheng JK, Liu YC, Ji RR.
Microglia: a promising target for treating neuropathic and postoperative pain, and morphine tolerance. 2011 Aug
J Formos Med Assoc.;110(8):487-94.
18. Lam CF, Roan JN, Lee CH, Chang PJ, Huang CC, Liu YC, Jiang MJ, Tsai YC
Transplantation of endothelial progenitor cells improves pulmonary endothelial function and gas exchange in rabbits with endotoxin-induced acute lung injury
Anesth Analg. 2011 Mar;112(3):620-7
19. Gao Y J, Z. Z. Xu, ZZ, Liu YC , Wen YR, Decosterd I, Ji RR
The c-Jun N-terminal kinase 1 (JNK1) in spinal astrocytes is required for the maintenance of bilateral mechanical allodynia under a persistent inflammatory pain condition. 2010 Feb
Pain 148(2): 309-19.
|
Patent List:
US Patent-2016/6
Treatment of inflammatory pain using IL-20 antagonists
Patent No.:US9,376,490 B2
Ming-Shi Chang, Yen-Chen Liu, Meng-Ru Shen
|
