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劉彥青

 劉彥青 麻醉部基礎麻醉科主任               English

學經歷

國立陽明大學醫學系畢業
慈濟大學醫學研究所碩士
國立中山大學生物科學所博士
高雄榮民總醫院麻醉部主治醫師
成功大學醫學院麻醉學科助理教授、副教授
哈佛大學Brigham & Women’s Hospital麻醉部研究醫師
台灣麻醉醫學會理事/監事
台灣疼痛醫學會監事/秘書長


專長  一般麻醉, 神經阻斷
疼痛醫學、生理學

現任  成大醫院麻醉部基礎麻醉科主任
成功大學醫學院麻醉學科教授
台灣疼痛醫學會理事
麻醉學雜誌編輯
疼痛醫學雜誌主編

著作
(2010-)

1. HT Hsiao, YC Liu, PY Liu, SN Wu
Concerted suppression of Ih and activation of IK (M) by ivabradine, an HCN-channel inhibitor, in pituitary cells and hippocampal neurons.
Brain Research Bulletin. 2019 Apr 3;149:11-20.

2. YY Liu, HT Hsiao, JCF Wang, YC Liu, SN Wu
Parecoxib, a selective blocker of cyclooxygenase-2, directly inhibits neuronal delayed-rectifier K+ current, M-type K+ current and Na+ current.
European journal of pharmacology. 2019 Feb 5;844:95-101.

3. PC Wu, DB Shieh, HT Hsiao, JCF Wang, YC Lin, YC Liu
Magnetic field distribution modulation of intrathecal delivered ketorolac iron-oxide nanoparticle conjugates produce excellent analgesia for chronic inflammatory pain.
Journal of nanobiotechnology. 2018 May 16;16(1):49.

4. YC Lin, HT Hsiao, SN Wu, YC Liu
Huntington Mice Demonstrate Diminished Pain Response in Inflammatory Pain Model.
Anesthesia and analgesia. 2018 Feb;126(2):661-669.

5. PC Kuo, CJ Yang, YC Lee, PC Chen, YC Liu, SN Wu
The comprehensive electrophysiological study of curcuminoids on delayed-rectifier K+ currents in insulin-secreting cells.
European journal of pharmacology. 2018 Jan 15;819:233-241.

6. PC Wu, HT Hsiao, YC Lin, DB Shieh, YC Liu
The analgesia efficiency of ultrasmall magnetic iron oxide nanoparticles in mice chronic inflammatory pain model.
Nanomedicine: Nanotechnology, Biology and Medicine  2017 Aug;13(6):1975-1981.

7. Hung-Tsung Hsiao, Hsiao-Jung Chien, Ya-Chi Lin, Yen-Chin Liu.
Transcutaneous electrical nerve stimulator of 5000 Hz frequency provides better analgesia than that of 100 Hz frequency in mice muscle pain model.
Kaohsiung Journal of Medical Sciences (2017) 33, 165-170.

8. Hsiao HT, Lin YC, Wang JCF, Tsai YC, Liu YC.
Hypoxia inducible factor-1α inhibition produced anti-allodynia effect and suppressed inflammatory cytokine production in early stage of mouse complex regional pain syndrome model.
Clinical and Experimental Pharmacology and Physiology. 2016 Mar;43(3):355-9.

9. HT Hsiao, H Wu, PC Huang, YC Tsai, YC Liu.
The effect of propofol and sevoflurane on antioxidants and proinflammatory cytokines in a porcine ischemia-reperfusion model.
Acta Anaesthesiologica Taiwanica 54 (1), 6-10 2016.

10. Berta T, Park CK, Xu ZZ, Xie RG, Liu T, Lü N, Liu YC, Ji RR.
Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion.
J Clin Invest. 2014 Mar;124(3):

11. Berta T+,  Liu YC+, Xu ZZ,  Ji RR
Tissue plasminogen activator contributes to morphine tolerance and induces mechanical allodynia via astrocytic IL-1β and ERK signaling in the spinal cord of mice. 2013 Sep
Neuroscience. 2013;247:376-85  +These authors contributed equally to this work

12. Liu T, Berta T, Xu ZZ, Park CK, Zhang L, Lü N, Liu Q, Liu Y, Gao YJ, Liu YC, Ma Q, Dong X, Ji RR.
TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice.
J Clin Invest. 2012 Jun;122(6):2195-207

13. Liu YC, Wu PC, Shieh DB, Wu SN
The effects of magnetite (Fe3O4) nanoparticles on electroporation-induced inward currents in pituitary tumor (GH3) cells and RAW 264.7 macrophages. 2012 Mar
International Journal of nanomedicine 2012:7:1687-1696

14. Liu YC, Berta T, Liu T, Tan PH,Ji RR.
Acute morphine induces matrix metalloproteinase-9 up-regulation in primary sensory neurons to mask opioid-induced analgesia in mice
Mol Pain. 2012 Mar 25;8(1):19

15. Berta T, Liu T, Liu YC , Xu ZZ,Ji RR.
Acute morphine activates satellite glial cells and up-regulates IL-1beta in dorsal root ganglia in mice via matrix metalloprotease-9.
Mol Pain. 2012 Mar 22;8(1):18. doi: 10.1186/1744-8069-8-18.

16. Yeh CY, Chung SC, Tseng FL,Tsai YC, Liu YC.
Biphasic effects of chronic intrathecal gabapentin administration on the expression of protein kinase C gamma in the spinal cord of neuropathic pain rats.
Acta Anaesthesiol Taiwan. 2011 Dec;49(4):144-8.

17. Wen YR, Tan PH, Cheng JK, Liu YC, Ji RR.
Microglia: a promising target for treating neuropathic and postoperative pain, and morphine tolerance. 2011 Aug
J Formos Med Assoc.;110(8):487-94.

18. Lam CF, Roan JN, Lee CH, Chang PJ, Huang CC,  Liu YC, Jiang MJ, Tsai YC
Transplantation of endothelial progenitor cells improves pulmonary endothelial function and gas exchange in rabbits with endotoxin-induced acute lung injury
Anesth Analg. 2011 Mar;112(3):620-7

19. Gao Y J, Z. Z. Xu, ZZ, Liu YC , Wen YR, Decosterd I, Ji RR
The c-Jun N-terminal kinase 1 (JNK1) in spinal astrocytes is required for the maintenance of bilateral mechanical allodynia under a persistent inflammatory pain condition. 2010 Feb
Pain 148(2): 309-19.
 

專利
US Patent-2016/6
Treatment of inflammatory pain using IL-20 antagonists
Patent No.:US9,376,490 B2
Ming-Shi Chang, Yen-Chen Liu, Meng-Ru Shen

 


 

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